Mandelboim and his analysis collaborators discovered that the NKp46 receptor present on Organic Killer or NK cells play a crucial role in the advancement of the condition in mice. This is really because the NKp46 receptor recognizes pancreatic beta cells, resulting in their destruction. The study also demonstrated that inhibiting the NKp46 receptor almost completely prevented the advancement of diabetes. If replicated in human beings, this effect could considerably delay, and possibly prevent, the necessity for chronic insulin make use of by Type 1 diabetes sufferers, and help reduce diabetes-related problems. This groundbreaking research may be the basis for BioLineRx's BL-9020, a monoclonal antibody that targets the Organic Killer receptor NKp46.Earlier this full year, the NIH renewed a grant to Baylor Research Institute for $14.3 million. Three supplementary grants linked to this award and totaling $6.9 million were funded by the American Recovery and Reinvestment Work . The Institute also received an NIH award to review category B pathogens . This five-12 months $6.3 million grant will support collaborations between BIIR researchers and researchers from within the US and from Thailand, Mexico, Saudi Arabia, Macedonia, Spain, France and England.